Science’s gift to Diabetes: This drug will put it in reverse gear

NewsBharati    09-Apr-2018

California, April 9: Are you Diabetic? Then science has brought something for which can solve your problem and get rid you off from taking insulin etc. Researchers have found out a new drug which can completely reverse Diabetes.

A team of researchers, led by Stephanie Stanford at the University of California, San Diego, is proposing a solution in the form of a single pill that aims to restore insulin sensitivity in diabetic patients. Type 2 diabetes develops when the body’s response to insulin, the hormone responsible for regulating sugar in our blood, weakens. A number of genetic and lifestyle factors will influence whether or not someone develops this type of diabetes in their lifetime.

Up until now, drugs were unable to restore the insulin signaling function in diabetic patients — instead, they work by filtering out excess glucose in the blood that comes as a result of the dysfunction. The drug produced by Stanford’s team, on the other hand, hopes to restore function.

The drug inhibits an enzyme called low molecular weight protein tyrosine phosphatase (LMPTP), which is suspected to contribute to the reduction in cell sensitivity to insulin. With reduced LMPTP activity, the drug re-enables insulin receptors on the surface of cells — particularly those in the liver — which in turn restores the cell’s ability to regulate excess sugar. When the body can once again regulate blood sugar levels, the condition of Type 2 diabetes is effectively reversed.