Moscow, April 22: The world’s first successful combined transplantation of the lungs and kidney in a child with cystic fibrosis has been performed at the V.I. Shumakov Medical Research Center in Moscow, the centre’s chief, Sergei Gotie, told a news conference on Monday. Cystic fibrosis is a lifelong disease that affects the lungs and digestive system. Cystic fibrosis is a genetic disease. This means that people inherit it from their parents through genes (or DNA)
"I am pleased to present a unique clinical observation, which is the first not only in Russia but in the world, too - the first successful combined transplantation of three organs performed in a child," Gotie said.
The Shumakov Center’s press-service said the nine-year-old patient, Mikhail, from a village in Sakhalin, was diagnosed with the cystic fibrosis - a genetic disorder that affects several organs at a time, lungs in the first place. Also, the boy had liver cirrhosis.
Doctors aim is early detection of renal impairment in children with Cystic fibrosis and hence doctors can do careful monitoring, close follow up and adjustment of medications. Cystic fibrosis transmembrane conductance regulator (CFTR) gene abnormalities in Indian males with congenital bilateral absence of vas deferens & renal anomalies are observed.
Routine monitoring and early intervention (antibiotics, high calorific intake, pancreatic enzymes and physiotherapy) have increased the life expectancy of cystic fibrosis (CF) patients from 14 years in 1969 to 30 years in 1995. Renal function is not affected primarily in CF (except for a reduced capacity to secrete sodium chloride), but the kidney may be involved secondarily in later life. With the increasing numbers of CF patients receiving a lung or a lung or heart, doctors faced challenges for this disorder.
People with CF can have a variety of symptoms, including:
Daily cough, at times with mucus
Shortness of breath
Poor growth or slow weight gain even with a good appetite
Frequent greasy, bulky, foul-smelling stools or trouble having a bowel movement